Blar i forfatter "Ervik, Ida Korsnes"
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Presence of high-endothelial venules correlates with a favorable immune microenvironment in oral squamous cell carcinoma
Wirsing, Anna Maria; Ervik, Ida Korsnes; Seppola, Marit; Uhlin-Hansen, Lars; Steigen, Sonja Eriksson; Hadler-Olsen, Elin Synnøve (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-02-07)Oral squamous cell carcinomas are associated with a poor prognosis, which may be partly due to functional impairment of the immune response. Lymphocyte recruitment to the tumor site is facilitated by high-endothelial venules, whereas expression of programmed-death ligand 1 (PD-L1) can impair T-cell function. Thus, we hypothesize that these factors are important in shaping the immune response in oral ... -
Presence of high-endothelial venules correlates with a favorable immune microenvironment in oral squamous cell carsinoma
Wirsing, Anna Maria; Ervik, Ida Korsnes; Seppola, Marit; Uhlin-Hansen, Lars; Steigen, Sonja Eriksson; Hadler-Olsen, Elin (Master thesis; Mastergradsoppgave, 2017-10-31)Oral squamous cell carcinomas (OSCC) are associated with a poor prognosis, which may be partly due to functional impairment of the immune response. Lymphocyte recruitment to the tumor site is facilitated by high-endothelial venules (HEV), whereas expression of programmed-death ligand 1 (PD-L1) can impair T cell function. Thus, we hypothesize that these factors are important in shaping the immune ...